Environmental aspects Avilamycin is rapidly hydrolysed under acid conditions but degrades more slowly under alkaline and neutral conditions. It is rapidly degraded by photolysis. Based on data from field dissipation studies avilamycin appeared to degrade fairly readily in soil with a half-life, for disappearance of a radioactive label, in the order of 3-4 weeks. Most of the faecal radioactivity was unchanged avilamycin which accounted for approximately 50% of the radioactive residue. Leaching Removal of a compound by use of a solvent. The target tissue for chickens was the liver.
The product should not be used in laying birds where eggs or egg products are to be used for human consumption or processing. Biosynthetic gene cluster of the non-ribosomally synthesized cyclodepsipeptide skyllamycin: deciphering unprecedented ways of unusual hydroxylation reactions. J. Am. Chem. Poultry Chickens pretreated by feeding with unlabelled avilamycin followed by a single dose of 14C-avilamycin excreted most of the dose within 4 days with greater than 50% excreted in the first 24 hours post dose.
Codex MRL Internationally published standard maximum residue limit. Mining of in-house-sequenced Streptomyces genomes revealed a novel nonribosomal peptide biosynthetic gene cluster in S. calvus (ATCC No. 13382). The corresponding gene cluster was uploaded to the GNP server to generate an automated structure prediction. Toxicology The study of the nature and effects of poisons. Few reports deal with the effects of anaerobic incubation on MIC results. These strains were not included in the comparative tables. The results indicated that percent mortality was slightly higher in the avilamycin treated group than the group treated with virginiamycin but both treated groups had significantly lowered mortality compared to the untreated group.